Exosomes: The Unseen Players in Neurodegenerative Diseases

Exosomes: The Unseen Players in Neurodegenerative Diseases

Introduction Once thought to be mere cellular debris, exosomes have emerged as significant players in neurodegenerative diseases. These extracellular vesicles, ranging from 30 to 100 nm in size, are produced by all cell types in the central nervous system (CNS). Far from being simple waste disposal units, exosomes are involved in complex intercellular communication and…

Donanemab Results in Cognitive Decline in Alzheimer's Disease

Donanemab Shows Promising Results in Slowing Cognitive Decline in Alzheimer’s Disease

Introduction Eli Lilly recently presented the full results from their Phase 3 TRAILBLAZER-ALZ 2 study at the Alzheimer’s Association International Conference (AAIC). The study focused on evaluating the effectiveness of donanemab, a potential treatment for early symptomatic Alzheimer’s disease (AD). The results, also published in the Journal of the American Medical Association (JAMA), demonstrated that…