Biotech Blog(Page 4)

Biotech Blog

alzheimers-tau-biomarker-testing-partner
What should you require from an Alzheimer's tau biomarker testing partner?
Plasma p-tau217 now separates amyloid-positive from amyloid-negative patients about as well as a lumbar...
Scientist analyzing blood samples for an ALS biomarker clinical trial
Three Gates Between an ALS Biomarker and a Trial Endpoint
Most ALS biomarker conversations start with the wrong question. Which marker should we measure? The more...
Blood samples and clinical trial protocol illustrating companion diagnostic development for blood-based CNS biomarker
Companion Diagnostic Development on a Blood-Based CNS Biomarker
A Phase II readout comes back flat. Someone reruns the analysis on the biomarker-defined subgroup, and...
Lewy body dementia clinical trial biomarkers
Lewy Body Dementia: Building a Blood Biomarker Strategy Without Serial CSF
A sponsor opening a phase 2 trial in Lewy body dementia faces a problem that has nothing to do with assay...
Brain-Specific Biomarker Analysis in CNS Clinical Trials
How Do You Add a Brain-Specific Biomarker to a Trial Panel?
Adding a Tissue-of-Origin Biomarker to an Existing Trial Panel Brain-Specific Biomarker A Phase II readout...
Illustration of a person with Parkinson’s disease showing the brain and neuronal pathology associated with biomarker selection for clinical trials.
How to Select Blood Biomarkers for a Parkinson's Trial
Two Phase II α-synuclein antibody programs read out in the same issue of the same journal in 2022. Both...
Blood sample for Alzheimer’s biomarker discovery in a neuroscience research laboratory.
Biomarker Discovery for Alzheimer's Drug Programs: What Blood-Based Platforms Can Add
Lecanemab and donanemab proved that amyloid-clearing drugs can slow decline — and proved something else...
CNS target engagement using blood-based neuron-derived extracellular vesicle biomarkers
Measuring CNS Target Engagement Without a Spinal Tap
CNS target engagement  Key TakeawaysLumbar puncture is safe on average, but its logistics — not its...
Alpha-Synuclein Target Engagement
Alpha-Synuclein Target Engagement: What CSF and Imaging Can't Show You
Alpha-Synuclein Target Engagement Two alpha-synuclein-targeting antibodies reached Phase 2 with strong...
Scientist performing CNS biomarker testing in a modern laboratory for neurology clinical trial biomarker analysis.
What to Demand From a CNS Biomarker Service Provider
Selecting a CNS biomarker service provider? Learn the four criteria that matter most: regulatory validation,...
1 2 3 4 5 6
Back to top Drag