LogoLuminEV

LuminEV Kit for multiplexed analysis of EV surface proteins in plasma and cell culture media without prior EV isolation (CD9, CD63, CD81).

Cat. No./ID 001-96

Price:  $2,500 (1 X 96-Well Plate)

                $11,250 (5 X 96-Well Plates)

                $40,000 (20 X 96-Well Plates) 

                Customized kit (ask for a quote)   

General description

LuminEV is an advanced research kit designed to analyze extracellular vesicles (EVs) comprehensively. It enables researchers to examine the surface protein composition of EVs, offering high sensitivity, multiplexed analysis, and compatibility with unprocessed samples. This innovative tool is valuable for understanding EV biology, biomarker discovery, quality control of therapeutic EVs, and large-scale studies across various research fields.

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Assay Manual

Applications

  • EV population analysis: identification of EV sub-populations based on surface protein profiles.
  • Large-Scale Studies:  can be used in large population studies to assess EV surface proteins across diverse samples.
  • EV secretion analysis: screening of compounds that modulate EV release in a 96-well format.
  • Basic Research: facilitates easier characterization for in-depth analysis of EV biology and function.
  • Biomarker Discovery:  aids in identifying EV-based disease biomarkers and provides normalization parameters.
  • Therapeutic EV Quality Control: suitable for quality control analysis of therapeutic EVs, ensuring standardized production.

Sample Compatibility

Plasma, cell culture media, purified EVs.

 Advantages

  • Multiplexed Analysis:  enables researchers to assess multiple EV surface proteins in a comprehensive manner. This saves time and precious sample volume.
  • Compatibility with Unprocessed Samples:  compatible with unprocessed cell culture media and blood plasma samples. This eliminates the need for time-consuming and potentially bias-inducing EV isolation procedures, simplifying the workflow and reducing the risk of altering EV composition during isolation.
  • Throughput capabilities: performed in a 96-well format with less than 5 hours of hands-on time.
  • Colocalization Analysis:  can be used to identify the colocalization of different surface markers on the same EV.
  • Sensitivity and Specificity: capable of detecting low levels of EV surface proteins. This is crucial when working with limited sample volumes. Shows high specificity in detecting EV surface markers.
  • Precision and Dynamic Range: demonstrates excellent precision (CV below 15%) and offers a wide dynamic range.

 

Product specifications

 

LuminEV kit
This product(s), is FOR RESEARCH USE ONLY and is not to be used for any medical purpose or objective (For EU see MEDDEV 2.14/2, for U.S. see relevant FDA guidance document). By ordering or using this product you hereby acknowledge that the products are labeled and intended FOR RESEARCH USE ONLY and NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC, OR CLINICAL PROCEDURES and agree that you shall only use the product for your research use. This product may not be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses, or any type of consumption or application to humans or animals.

Advantages

Multiplex capabilities

Throughput capabilities

User-friendly

No need for EV isolation

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